Cytoxan and sperm

Fertility refers to having the ability to conceive, or being able to have a child. For males, fertility means they are able to father a child through normal sexual activity. A person's fertility depends on their reproductive organs working as they should and other factors, such as when and how often they are having sex, certain hormones, and if their partner has any problems with fertility. When a person cannot have a child, this is called infertility , or being infertile. For males, infertility means they are not able to father a child through normal sexual activity. Doctors usually consider a person infertile when they have not been able to conceive a child after 12 or more months of regular sexual activity.
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How Cancer And Cancer Treatment Can Affect Fertility in Males

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Can I Have Children After Cancer Treatments? (for Teens) - Nemours Kidshealth

Chemotherapy , radiation therapy , and other treatments can be very effective at doing their job. But what makes them good at fighting cancer or other illnesses also can cause side effects : As these treatments attack harmful cells, they may affect some healthy cells too. Your doctor has probably talked about whether you'll have any side effects from your cancer treatment. Side effects like reduced fertility all depend on your diagnosis, the type of treatment you're getting, and the doses of medicines or radiation. Everyone is different, so it's best to bring any questions or worries up with your medical team. Your doctor can tell you if there's a chance that cancer treatment might affect your reproductive organs.
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Can I Have Children After Cancer Treatments?

Cyclophosphamide continues to have an important role in the treatment of renal disease, including nephrotic syndrome and lupus nephritis, despite known complications of gonadotoxicity and potential infertility in both male and female patients. It is important that the physician recommending this therapy mitigates the effect of the drug on fertility by adhering to recommendations on dosing limits and offering fertility-preserving strategies. In addition to well-established methods, such as sperm banking and embryo cryopreservation, advances in reproductive technology have yielded strategies such as oocyte cryopreservation, resulting in more fertility-preserving options for the pediatric patient.
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The cyclophosphamide is used in cancer treatment. The aim of this study was evaluating the effect of different doses of this drug on male mice reproductive parameters. The cyclophosphamide was administered in the doses , , e mg. As a result, it was observed a decrease in body mass and a decrease in testicles and kidney's weight, in all animals treated with cyclophosphamide. Only the groups that received the doses , mg.
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